The Truth About L-Ascorbic Acid Trio

The Truth About L-Ascorbic Acid Trio

L-Ascorbic Acid (LAA) is a form of Vitamin C which is commonly known for its instability in nature despite being one of the most trusted brightening ingredients in skincare. LAA has a fragile chemical structure as it degrades easily upon contact with light and air as well as exposure to high temperatures.

Imagine having a very delicate and emotionally unstable friend and only certain people can cope with this kind of person to neutralize the sensitive air. Of course, just like having a sensitive friend, the “emotional” L-Ascorbic Acid needs some friends to help it calm down and stabilize its compound.

The Founder of the Best Friends to L-Ascorbic Acid

To determine the best friends of L-Ascorbic Acid, a researcher named Dr Sheldon R. Pinnell pioneered the early research on the use of Vitamin C (Ascorbic Acid) on skin. He made the evolution of topical antioxidants by becoming the first person who patents the stable form of Vitamin C.

As the founding father of topical antioxidants, his findings had proven that topical Vitamin C is extremely beneficial in creating healthy skin. With more than 100 peer-reviewed publications about topical Vitamin C, he also co-founded SkinCeuticals and was the important formulator behind the signature C E Ferulic Serum.

DR. Pinnell Years of Research on Ascorbic Acid


  • Dr Pinnell started his first study of Ascorbic Acid in the year 2001 when he found out that the ingredient has the most effective penetration into the skin at pH below 3.5.
  • His second finding in the same year was the fact that Ascorbic Acid must have a concentration between 5% and 30% to be effective. Maximum penetration was seen with 20% Ascorbic Acid at pH 3.2 (1100 pmol/mg of skin).


Based on the picture above, it is proven that the formulation is effective in decreasing thymine dimer mutations, thereby helping to prevent the appearance of premature ageing and skin cancer.

L-Ascorbic Acid w/ Ferulic Acid & Vitamin E in Current Skincare

Today, the work of Dr Pinnell and his fellow scientists inspires the research on L-Ascorbic Acid, a-Tocopherol or Ferulic Acid. Other researchers continue to show the synergistic combination combats signs of ageing by protecting skin against environmental damage, restricts the development of malignant skin tumours, reduces pigmentation and aids in the recovery of post-laser redness.

L-Ascorbic Acid w/ Ferulic Acid & Vitamin E with Worthee Cosmetics

With all the benefits mentioned above, we are proud to share the products which contain this Worthee featured ingredients.

Geek & Gorgeous C-Glow 15% Vitamin C E Ferulic Acid Serum is a lightweight, yet power-packed vitamin liquid serum. It has the gorgeous benefits of visibly transforming and invigorating skin brightness, smoothness, and overall youthfulness. This would be a perfect choice for anyone searching for a pure Vitamin C serum with an effective delivery system that targets discolourations and ageing concerns.

Paula's Choice RESIST C15 Super Booster is a concentrated, light-as-water liquid treatment product designed to supercharge your serums, or it may be used alone. A blend of 15% stabilized vitamin C (L-Ascorbic Acid) at a pH of 3.0, antioxidant Vitamin E, Ferulic Acid, and Peptides repairs visible signs of ageing and stimulates collagen production for smoother, brighter, and firmer skin.


Timeless 20% Vitamin C + E + Ferulic Acid Serum is a highly-concentrated serum that will boost skin’s radiance to reveal its natural translucent glow while providing advanced protection against future discolourations from environmental damage. Light as water, this potent serum is formulated for all skin types with concerns for uneven skin tone and signs of ageing, or for anyone who wants to experience the benefits of active vitamin C. This product also would be appropriate for breakout-prone skin.

Now, you already know what's behind the history of these three iconic combo; L-Ascorbic Acid, Ferulic Acid and Vitamin C. Let us know your thoughts on this combination by commenting below!



Darr, Douglas & Dunston, Stan & Faust, H & Pinnell, S. (1996). Effectiveness of antioxidants (Vitamin C and E) with and without sunscreens as topical photoprotectants. Acta dermato-venereologica. 76. 264-8.

Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., Monteiro-Riviere, N. A., Grichnik, J. M., Zielinski, J., & Pinnell, S. R. (2005). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. The Journal of investigative dermatology, 125(4), 826–832.

Lin, Jing-Yi & Selim, M & Shea, Christopher & Grichnik, James & Omar, Mostafa & Monteiro-Riviere, Nancy & Pinnell, Sheldon. (2003). UV photoprotection by combination topical antioxidants vitamin C and E. Journal of the American Academy of Dermatology. 48. 866-74. 10.1067/mjd.2003.425.

Madey, Doren & Pinnell, Sheldon. (2010). Using topical antioxidants to protect against photodamage and improve skin care. Operative Techniques in Oculoplastic. Orbital and Reconstructive Surgery. 62-64. 10.1076/otoo.

Murray, John & Burch, James & Streilein, Robert & Iannacchione, Mary & Hall, Russell & Pinnell, Sheldon. (2008). A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human against damage caused by ultraviolet irradiation. Journal of the American Academy of Dermatology. 59. 418-25. 10.1016/j.jaad.2008.05.004.

Oresajo, Christian & Stephens, Thomas & Hino, dj & Law, Robert & Yatskayer, Margarita & Foltis, Peter & Pillai, Sreekumar & Pinnell, Sheldon. (2009). Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin. Journal of cosmetic dermatology. 7. 290-7. 10.1111/j.1473-2165.2008.00408.x.

Pinnell, Sheldon & Yang, Huanshu & Omar, Mostafa & Monteiro-Riviere, Nancy & Debuys, Holly & Walker, Linda & Wang, Yaohui & Levine, Mark. (2001). Topical L-Ascorbic Acid. Dermatologic Surgery. 27. 137-142. 10.1097/00042728-200102000-00008.

Topical L-Ascorbic Acid Percutanous Absorption Studies Pinnell, S.R., et al.,Topical L-Ascorbic Acid: Percutaneous Absorption Studies. Dermatol Surg 27:2, 137-142, 2001


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